Dr. Manji is an Assistant Professor of Medicine at Columbia University Medical Center. He received his M.D. from Ross University School of Medicine in 2009, completed his residency in internal medicine at Albany Medical College, and fellowship in Hematology/Oncology at NYPH-Columbia focusing on GI malignancies, melanoma, and sarcoma.
Research Team
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Translational medicine is a multidisciplinary field of research that aims to bridge the gap between scientific discoveries and clinical applications. It involves the translation of laboratory discoveries into new drugs, diagnostics, and therapies that can be used to prevent, diagnose, or treat diseases.The process of translational medicine involves several stages, including basic research, preclinical studies, clinical trials, and regulatory approval. It involves collaboration between scientists, clinicians, industry partners, and regulatory agencies to ensure that the results of laboratory studies are translated into safe and effective treatments for patients.Translational medicine has the potential to accelerate the development of new treatments and improve patient outcomes by providing a more efficient and effective approach to drug discovery and development. It also has the potential to reduce healthcare costs by identifying and addressing the root causes of diseases and developing targeted therapies that are tailored to individual patients.
Coming soon ...
Our team on PubMed
Check out our latest publications including articles and abstracts on National Library of Medicine.
The CXCR4/CXCL12 axis is a key immune evasion mechanism thought to deter CD8+ T-cells from infiltrating the tumor. We performed a large seven arm survival and biopsy/necropsy study in mice where we demonstrate that addition of gemcitabine to CXCR4 inhibition in combination with ICB, enhanced tumor stabilization and neoplastic cell death, and improved survival by 50 percent.
Our Collaborators
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Assistant Professor of Medicine at the CUIMC. His aim is to dissect interactions of cancer and immunity in the tumor development, metastasis and drug resistance.
